To give you some inspiration, here are several recipes to help you out: Lutein appears to be nontoxic and safe for consumption in moderate or even relatively high doses. View abstract. Int J Sport Nutr Exerc Metab 2005;15:401-12. 2001;42(8):1873-1881. View abstract. Note that the numbers in parentheses (1, 2, etc.) VandenLangenberg GM, Mares-Perlman JA, Klein R, et al. View abstract. View abstract. View abstract. View abstract. Invest Ophthalmol.Vis.Sci. Since the plant Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy: a pilot study. View abstract. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. View abstract. View abstract. Relation among serum and tissue concentrations of lutein and zeaxanthin and macular pigment density. Dwyer, J. H., Navab, M., Dwyer, K. M., Hassan, K., Sun, P., Shircore, A., Hama-Levy, S., Hough, G., Wang, X., Drake, T., Merz, C. N., and Fogelman, A. M. Oxygenated carotenoid lutein and progression of early atherosclerosis: the Los Angeles atherosclerosis study. Photochem.Photobiol. Giving preterm infants lutein and zeaxanthin by mouth doesn't prevent retinopathy of prematurity. A. Serum carotenoids and alpha-tocopherol and risk of nonmelanoma skin cancer. 2012;131(1):239-253. Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007-2012. Astaxanthin is a red pigment that belongs to a group of chemicals called carotenoids. Am J Clin Nutr 2000;71:575-82. Nutrition 2012;28(6):605-610. View abstract. Furosemide: 2 people, J Am Optom Assoc 1999;70:39-47. Koh HH, Murray IJ, Nolan D, et al. Capeding, R., Gepanayao, C. P., Calimon, N., Lebumfacil, J., Davis, A. M., Stouffer, N., and Harris, B. J. Lutein-fortified infant formula fed to healthy term infants: evaluation of growth effects and safety. Also known as Dorgan, J. F., Boakye, N. A., Fears, T. R., Schleicher, R. L., Helsel, W., Anderson, C., Robinson, J., Guin, J. D., Lessin, S., Ratnasinghe, L. D., and Tangrea, J. Rock, C. L., Thornquist, M. D., Neuhouser, M. L., Kristal, A. R., Neumark-Sztainer, D., Cooper, D. A., Patterson, R. E., and Cheskin, L. J. Effects of supplemental beta-carotene , cigarette smoking, and alcohol consumption on serum carotenoids in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. 2010;21(6):544-549. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Lutein has no known severe, serious, moderate, or mild interactions with other drugs. This information does not contain all possible interactions or adverse effects. Parenteral nutrition with branched-chain amino acids in hepatic encephalopathy. Supplementation with carotenoids, omega-3 fatty acids, and vitamin E has a positive effect on the symptoms and progression of Alzheimer's disease. The ARIC Study Investigators. (Tokyo) 2009;55(6):479-485. Zeimer, M. B., Kromer, I., Spital, G., Lommatzsch, A., and Pauleikhoff, D. Macular telangiectasia: patterns of distribution of macular pigment and response to supplementation. Arterioscler.Thromb.Vasc.Biol 2004;24(2):313-319. A., Fisher, A. I., Klein, R., Palta, M., Block, G., Millen, A. E., and Wright, J. D. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Handelman, G. J., Nightingale, Z. D., Lichtenstein, A. H., Schaefer, E. J., and Blumberg, J. Ophthalmology 2008;115(5):876-883. View abstract. The recommended lutein dosage for preventing oxidative damage and lowering symptoms of eye or skin disorders isbetween 6 milligrams and 30 milligrams daily for adults, according to the American Macular Degeneration Association. Ophthalmology 2012;119(11):2282-2289. Acta Ophthalmol Scand 1997;75:634-40. Snellen, E. L., Verbeek, A. L., Van Den Hoogen, G. W., Cruysberg, J. R., and Hoyng, C. B. Neovascular age-related macular degeneration and its relationship to antioxidant intake. View abstract. 2013;73(2):236-45. View abstract. Nutr Cancer 1998;32(3):154-158. J Nutr 2004;134:2387-94. Ma, L., Dou, H. L., Wu, Y. Q., Huang, Y. M., Huang, Y. A. In addition, reduced Several studies 2014 May;174(5):763-71. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Skin Pharmacol.Physiol 2007;20(4):199-210. View abstract. Goodman GE, Schaffer S, Omenn GS, et al. 2002;132(3):525S-530S. Riccioni, G., Speranza, L., Pesce, M., Cusenza, S., D'Orazio, N., and Glade, M. J. View abstract. View abstract. Duncan, J. L., Aleman, T. S., Gardner, L. M., De Castro, E., Marks, D. A., Emmons, J. M., Bieber, M. L., Steinberg, J. D., Bennett, J., Stone, E. M., MacDonald, I. M., Cideciyan, A. V., Maguire, M. G., and Jacobson, S. G. Macular pigment and lutein supplementation in choroideremia. Reboul E, Thap S, Perrot E, et al. Maternal lutein and zeaxanthin concentrations in relation to offspring visual acuity at 3 years of age: The GUSTO Study. Arch.Biochem.Biophys. At this time there isnt a general recommendation for daily intake of lutein or zeaxanthin. Eye Disease Case-Control Study Group. 2009;41(9):1752-1760. Coyne, T., Ibiebele, T. I., Baade, P. D., Dobson, A., McClintock, C., Dunn, S., Leonard, D., and Shaw, J. Diabetes mellitus and serum carotenoids: findings of a population-based study in Queensland, Australia. Just like with the previously mentioned studies that show potential cancer-protective effects of this carotenoid, we arent exactly sure yet how it improves heart health. WebShop 12 Hour Mucus Relief DM Extended-Release Tablets Maximum Strength and read reviews at Walgreens. 2 mg of copper. Am.J.Clin.Nutr. Can.J.Ophthalmol. Qiu Z, Chen X, Geng T, et al. Lutein /zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. Yagi, A., Fujimoto, K., Michihiro, K., Goh, B., Tsi, D., and Nagai, H. The effect of lutein supplementation on visual fatigue: a psychophysiological analysis. Glabska D, Guzek D, Zakrzewska P, Lech G. Intake of Lutein and Zeaxanthin as a Possible Factor Influencing Gastrointestinal Symptoms in Caucasian Individuals with Ulcerative Colitis in Remission Phase. An eye disorder in premature infants that can lead to blindness (retinopathy of prematurity). View abstract. Lyle BJ, Mares-Perlman JA, Klein BE, et al. Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year. View abstract. Ask yourself this question: How many colors are in your favorite foods? Ito, Y., Wakai, K., Suzuki, K., Tamakoshi, A., Seki, N., Ando, M., Nishino, Y., Kondo, T., Watanabe, Y., Ozasa, K., and Ohno, Y. Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study. When we eat foods high in lutein or take it in supplement form, its believed to be pretty easily transported around the body, especially to the parts of the eyes called the macula and the lens. J Nutr 1998;128:1920-6.. View abstract. Xu J, Song C, Song X, Zhang X, Li X. Carotenoids and risk of fracture: a meta-analysis of observational studies. Calendula is often marketed as a treatment for eczema and dermatitis, but there is not much research supporting its effectiveness for these conditions. View abstract. 8-15-2012;92(10):2043-2049. Br J Nutr 2001;85(2):227-238. View abstract. 2005 - 2023 WebMD LLC. View abstract. Cancer Epidemiol.Biomarkers Prev. 2014 Jan;252(1):63-70. Ophthalmology 2011;118(10):1958-1965. View abstract. PLoS One 2019;14(12):e0227048. Mares-Perlman JA, Brady WE, Klein R, et al. View abstract. Lutein is a type of carotenoid with strong antioxidant properties that have been shown to be beneficial for eye health, cognitive function, and heart health and may even Juturu V, Bowman JP, Deshpande J. Cangemi, F. E. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. Epidemiology 2004;15(6):738-745. B. Lutein and zeaxanthin concentrations in plasma after dietary supplementation with egg yolk. Treatment of Macular Telangiectasia Type 2 With Carotenoid Supplements Containing Meso-Zeaxanthin: A Pilot Study. Am J Clin Nutr 2000;71:1187-93. It is certified by the National Eczema Association, meaning it is safe for those with eczema or sensitive skina testament to its mildness. J Am Coll Nutr 2001;20(3):232-238. Jacques, P. F., Chylack, L. T., Jr., Hankinson, S. E., Khu, P. M., Rogers, G., Friend, J., Tung, W., Wolfe, J. K., Padhye, N., Willett, W. C., and Taylor, A. Int J Vitam Nutr Res 1998;68:360-5. Rock, C. L., Flatt, S. W., Wright, F. A., Faerber, S., Newman, V., Kealey, S., and Pierce, J. P. Responsiveness of carotenoids to a high vegetable diet intervention designed to prevent breast cancer recurrence. 2004;13(8):1276-1282. View abstract. The risk of vision loss decreased by 19%. View abstract. View abstract. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. J.Nutr. Optometry 2000;71:147-64.. View abstract. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Manzoni P, Guardione R, Bonetti P, et al. Am J Hypertens. Br.J Nutr 1999;82(3):203-212. Mahmassani HA, Switkowski KM, Scott TM, et al. Br J Nutr 2001;85(4):499-507. Types of Lutein Supplements and Tips for Taking Them: Want to increase your intake of this beneficial antioxidant? A prospective study of carotenoid intake and risk of cataract extraction in US men. Sommerburg, O. G., Siems, W. G., Hurst, J. S., Lewis, J. W., Kliger, D. S., and van Kuijk, F. J. Lutein and zeaxanthin are associated with photoreceptors in the human retina. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Both older and younger people should consume plenty of lutein in order to reduce the risk of oxidative damage that can lead to disorders down the road. View abstract. Creatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trial. Am.J.Epidemiol. View abstract. Kotagiri SR, Morde A, Rai D, et al. 3-1-2001;153(5):424-432. Lyle, B. J., Mares-Perlman, J. A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. 2012;56(1):126-146. Morganti, P., Fabrizi, G., and Bruno, C. Protective effects of oral antioxidants on skin and eye function. View abstract. Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy: a retrospective study. Information from this source is evidence-based and objective, and without commercial influence. Schweiggert, R. M., Mezger, D., Schimpf, F., Steingass, C. B., and Carle, R. Influence of chromoplast morphology on carotenoid bioaccessibility of carrot, mango, papaya, and tomato. View abstract. 2006;90(7):927-928. Plant foods and colon cancer: an assessment of specific foods and their related nutrients (United States). Neuroepidemiology. Make sure to readlutein and zeaxanthin supplements review ratings to ensure you get the best antioxidant eye health supplements. View abstract. View abstract. View abstract. Ophthalmic Res. Vojnikovic, B., Kovacevic, D., Njiric, S., and Coklo, M. Long term results of age-related macular degeneration therapy with prednisolone acetate--special refer to peripheral visual field changes. Product Details: and antioxidant-rich lutein, which protects against blue-light-induced skin aging. The first 200 years. The major reason the lens becomes cloudy is damage due to oxidation. Retina 2010;30(8):1282-1293. Changes in plasma amino acid patterns in chronic alcoholic patients during ethanol withdrawal syndrome: their clinical implications. 2001;42(2):439-446. Regul.Toxicol Pharmacol 2006;45(3):289-298. Am.J.Clin.Nutr. 2008;49(8):3328-3335. The association between lung and prostate cancer risk, and serum micronutrients: results and lessons learned from beta-carotene and retinol efficacy trial. By performing a macular pigment optical density test (MPOD), doctors can better give specialized dietary recommendations for protective nutrients based on individual responses, genetic predisposition and lifestyle factors. With dry eye disease, also known as dry eye syndrome, your eyes dont make enough lubrication to coat your eyes. This can cause red, itchy, burning, eyes, temporary blurriness, and a feeling as if theres sand in your eye. According to a 2016 study, lutein may help reduce these symptoms. How much lutein do you need? Hammond, B. R., Jr. and Fletcher, L. M. Influence of the dietary carotenoids lutein and zeaxanthin on visual performance: application to baseball. Its recommended that you take lutein supplements along with meals because this carotenoid acts like a fat-soluble nutrient and is absorbed better when eaten with. Role of lutein supplementation in the management of age-related macular degeneration: meta-analysis of randomized controlled trials. A. Richer, S. ARMD--pilot (case series) environmental intervention data. View abstract. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. J.Ocul.Pharmacol.Ther. View abstract. View abstract. View abstract. Am J Perinatol. . CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. View abstract. Nutr.J. San Giovanni, J. P., Chew, E. Y., Clemons, T. E., Ferris, F. L., III, Gensler, G., Lindblad, A. S., Milton, R. C., Seddon, J. M., and Sperduto, R. D. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. J Nutr 2004;134:1887-93. Coll.Antropol. Sumantran, V. N., Zhang, R., Lee, D. S., and Wicha, M. S. Differential regulation of apoptosis in normal versus transformed mammary epithelium by lutein and retinoic acid. Am J Clin Nutr 2012;96(2):356-373. Zinc is an important mineral that plays a key role in skin health (17). View abstract. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Lutein and zeaxanthin status and risk of age-related macular degeneration. A., Klein, B. E., Klein, R., Palta, M., Bowen, P. E., and Greger, J. L. Serum carotenoids and tocopherols and incidence of age-related nuclear cataract. View abstract. A., de Vries, A. J., Goldbohm, R. A., Tijburg, L. B., Kardinaal, A. F., and van Poppel, G. Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin. View abstract. Early childhood lutein and zeaxanthin intake is positively associated with early childhood receptive vocabulary and mid-childhood executive function but no other cognitive or behavioral outcomes in project viva. Chen F, Hu J, Liu P, Li J, Wei Z, Liu P. Carotenoid intake and risk of non-Hodgkin lymphoma: a systematic review and dose-response meta-analysis of observational studies. View abstract. The pharmacological effects of quercetin, such as its antioxidant, anti-inflammatory, antiallergic, antiaging, and anticancer activities, as well as its regulating effect on interleukin (IL)-6, IL-8, tumor necrosis factor (TNF), histamine, and tryptase release in mast cells, are well acknowledged [9]. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Plasma antioxidant vitamins and carotenoids and age-related cataract. 2002;75(3):540-549. View abstract. View abstract. A., Meyer-Wenger, A., Moser, U., Wright, A., Southon, S., Thurnham, D., Chopra, M., van den, Berg H., Olmedilla, B., Favier, A. E., and Roussel, A. M. No significant effects of lutein, lycopene or beta-carotene supplementation on biological markers of oxidative stress and LDL oxidizability in healthy adult subjects. View abstract. However, at this time, more research is still needed to help us fully understand the effects of carotenoids on cancer, along with immune, hormonal and cardiovascular health, independent of other nutrients that are found in fruits and vegetables. Lutein is an antioxidant often used in the treatment or prevention of eye diseases. Traditionally lutein is characterized by its blue light filtering and anti-oxidant properties. 2008;87(6):1837-1843. Tan, J. S., Wang, J. J., Flood, V., Rochtchina, E., Smith, W., and Mitchell, P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. Nutrients 2020;12(2):274. Zhang Y, Knol LL, Tan L. Association between dietary lutein/zeaxanthin intake and metabolic syndrome among US females: An analysis of national health and examination surveys 2015-2018. A 2009 study conducted on diabetic rats found that supplementing with lutein and DHA (a crucial type of omega-3 fatty acid) helped normalize all diabetes-induced biochemical modifications. View abstract. Br.J.Nutr. 2011;94(5):1211-1218. SanGiovanni, J. P. and Neuringer, M. The putative role of lutein and zeaxanthin as protective agents against age-related macular degeneration: promise of molecular genetics for guiding mechanistic and translational research in the field. Retina 1981;1(4):296-310. Takeda, S., Masuda, Y., Usuda, M., Marushima, R., Ueji, T., Hasegawa, M., and Maruyama, C. Effects of mayonnaise on postprandial serum lutein/zeaxanthin and beta-carotene concentrations in humans. Lutein is best absorbed when taken with a View abstract. Lyle BJ, Mares-Perlman JA, Klein BE, et al. Goltz, S. R., Campbell, W. W., Chitchumroonchokchai, C., Failla, M. L., and Ferruzzi, M. G. Meal triacylglycerol profile modulates postprandial absorption of carotenoids in humans. Sabour-Pickett, S., Nolan, J. M., Loughman, J., and Beatty, S. A review of the evidence germane to the putative protective role of the macular carotenoids for age-related macular degeneration. Am.J.Clin.Nutr. View abstract. View abstract. Taylor, A., Jacques, P. F., Chylack, L. T., Jr., Hankinson, S. E., Khu, P. M., Rogers, G., Friend, J., Tung, W., Wolfe, J. K., Padhye, N., and Willett, W. C. Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities. Am.J.Clin.Nutr. Invest Ophthalmol.Vis.Sci. Invest Ophthalmol.Vis.Sci. View abstract. Martin, K. R., Failla, M. L., and Smith, J. C., Jr. Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage. Valero, M. P., Fletcher, A. E., De Stavola, B. L., Vioque, J., and Alepuz, V. C. Vitamin C is associated with reduced risk of cataract in a Mediterranean population. 2001;42(1):235-240. Iribarren, C., Folsom, A. R., Jacobs, D. R., Jr., Gross, M. D., Belcher, J. D., and Eckfeldt, J. H. Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. Am J Epidemiol 1998;148:204-14. 2014;42(1):25-38. Machida N, Kosehira M, Kitaichi N. Clinical effects of dietary supplementation of lutein with high bio-accessibility on macular pigment optical density and contrast sensitivity: A randomized double-blind placebo-controlled parallel-group comparison trial. JAMA. Eur.J.Clin.Nutr. View abstract. Li, L., Chen, C. Y., Aldini, G., Johnson, E. J., Rasmussen, H., Yoshida, Y., Niki, E., Blumberg, J. are clickable links to these studies. Olmedilla, B., Granado, F., Blanco, I., and Vaquero, M. Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study. Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy. Plasma kinetics of lutein, zeaxanthin, and 3-dehydro-lutein after multiple oral doses of a lutein supplement. Berson, E. L., Rosner, B., Sandberg, M. A., Weigel-DiFranco, C., Brockhurst, R. J., Hayes, K. C., Johnson, E. J., Anderson, E. J., Johnson, C. A., Gaudio, A. R., Willett, W. C., and Schaefer, E. J. 2007;78(5):213-219. Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. Am J Clin Nutr 1995;62:604-10. Invest Ophthalmol.Vis.Sci. View abstract. View abstract. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. 60 Count (Pack of 1) 4.5 4.5 out of 5 Nolan JM, Power R, Howard AN, et al. Long-term Outcomes of Adding Lutein/Zeaxanthin and ?-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28. View abstract. Nutr Neurosci 2021. Hammond BR Jr, Johnson EJ, Russell RM, et al. View abstract. Am J Clin Nutr. Siems, W. G., Sommerburg, O., and van Kuijk, F. J. Lycopene and beta-carotene decompose more rapidly than lutein and zeaxanthin upon exposure to various pro-oxidants in vitro. 2011;52(12):9207-9217. Skinmed. Hozawa, A., Jacobs, D. R., Jr., Steffes, M. W., Gross, M. D., Steffen, L. M., and Lee, D. H. Relationships of circulating carotenoid concentrations with several markers of inflammation, oxidative stress, and endothelial dysfunction: the Coronary Artery Risk Development in Young Adults (CARDIA)/Young Adult Longitudinal Trends in Antioxidants (YALTA) study. Int.J.Vitam.Nutr.Res. This eye vitamin isnt just beneficial for older adults taking preventative measures is the real key to preserving your vision and eye health. Just like many other types of antioxidants, it is found in brightly colored foods like fruits and vegetables especially leafy greens and types that are deep orange or yellow. J Sci Food Agric. A meta-analysis. View abstract. Ophthalmol Sci 2021;1(3):100039. 2013 Feb 15;5(2):543-51. 2012;53(12):7871-7880. Lutein, zeaxanthin and meso-zeaxanthin supplementation associated with macular pigment optical density. Effect of Dietary Supplementation With Lutein, Zeaxanthin, and ?-3 on Macular Pigment: A Randomized Clinical Trial. Cancer Epidemiol.Biomarkers Prev. 2001;119(7):1009-1019. Richer, S. P., Stiles, W., Graham-Hoffman, K., Levin, M., Ruskin, D., Wrobel, J., Park, D. W., and Thomas, C. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973. Bartlett, H. and Eperjesi, F. A randomised controlled trial investigating the effect of nutritional supplementation on visual function in normal, and age-related macular disease affected eyes: design and methodology [ISRCTN78467674]. View abstract. Ren YB, Qi YX, Su XJ, Luan HQ, Sun Q. Cancer Sci. Tan AC, Balaratnasingam C, Yannuzzi LA. Am J Epidemiol 2007;165(3):246-55. View abstract. Clin.Chem. This amount can be obtained pretty easily by eating a healthy andhealing diet(one cup of kale has more than22 milligrams), but supplements are also recommended for people who are highly susceptible to eye damage, those who have digestive disorders that can hinder nutrient absorption and the elderly, who could use more protection. Schupp C, Olano-Martin E, Gerth C, et al. Schunemann HJ, Grant BJ, Freudenheim JL, et al. Arch.Ophthalmol. Clin.Exp.Optom. Ophthalmic Surg Lasers Imaging Retina 2016;47(6):528-35. Aside from protecting eyes, lutein uses also include helping prevent skin disorders, several types of cancer including colon or breast cancer, type 2 diabetes, and risk factors associated with coronary heart disease. View abstract. Pool-Zobel, B. L., Bub, A., Muller, H., Wollowski, I., and Rechkemmer, G. Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Cardinault, N., Gorrand, J. M., Tyssandier, V., Grolier, P., Rock, E., and Borel, P. Short-term supplementation with lutein affects biomarkers of lutein status similarly in young and elderly subjects. Pickup & Same Day Delivery available on most store items. J Nutr 2021;151(3):615-627. Br J Nutr 2006;95(2):358-365. Wang X, Jiang C, Zhang Y, et al. Cardinault, N., Tyssandier, V., Grolier, P., Winklhofer-Roob, B. M., Ribalta, J., Bouteloup-Demange, C., Rock, E., and Borel, P. Comparison of the postprandial chylomicron carotenoid responses in young and older subjects. This information may not fit your specific health circumstances. Note that the numbers in parentheses (1, 2, etc.) Flood V, Smith W, Wang JJ, et al. View abstract. Invest Ophthalmol.Vis.Sci. J Nutr 2002;132:3668-73. Nutr Neurosci 2008;11(2):75-83. Diabetes Care 2022;45(6):1453-1461. View abstract. Maternal intake of lutein and zeaxanthin during pregnancy is positively associated with offspring verbal intelligence and behavior regulation in mid-childhood in the project viva cohort. J Lab Clin Med 1999;134(6):592-598. Sommerburg O, Keunen JE, Bird AC, van Kuijk FJ. Zhou Y, Wang T, Meng Q, Zhai S. Association of carotenoids with risk of gastric cancer: a meta-analysis. 2011;82(11):667-680. View abstract. Dietary modification of human macular pigment density. In addition to being found within thepigments of oureyes, carotenoids are also present within the skin. View abstract. View abstract. Medicine (Baltimore) 2019;98(29):e15404. Junghans, A., Sies, H., and Stahl, W. Macular pigments lutein and zeaxanthin as blue light filters studied in liposomes. Vegetables, fruit, and cancer. View abstract. View abstract. That said, possible lutein and zeaxanthin side effects can include harmless yellowingof the skin calledcarotenemia and an upset stomach/vomiting if you take too much. View abstract. Breast Cancer Res.Treat. Giordano, P., Scicchitano, P., Locorotondo, M., Mandurino, C., Ricci, G., Carbonara, S., Gesualdo, M., Zito, A., Dachille, A., Caputo, P., Riccardi, R., Frasso, G., Lassandro, G., Di, Mauro A., and Ciccone, M. M. Carotenoids and cardiovascular risk. View abstract. View abstract. Thomson, C. A., Stendell-Hollis, N. R., Rock, C. L., Cussler, E. C., Flatt, S. W., and Pierce, J. P. Plasma and dietary carotenoids are associated with reduced oxidative stress in women previously treated for breast cancer. JAMA Ophthalmol 2017;135(11):1259-1266. View abstract. Herron, K. L., McGrane, M. M., Waters, D., Lofgren, I. E., Clark, R. M., Ordovas, J. M., and Fernandez, M. L. The ABCG5 polymorphism contributes to individual responses to dietary cholesterol and carotenoids in eggs. 2002;56(7):615-621. Zhao, X., Aldini, G., Johnson, E. J., Rasmussen, H., Kraemer, K., Woolf, H., Musaeus, N., Krinsky, N. I., Russell, R. M., and Yeum, K. J. Glucosamine: 2 people, 18.18%. Astaxanthin supplementation does not attenuate muscle injury following eccentric exercise in resistance-trained men. 1996;66(2):119-125. Mahmassani HA, Switkowski KM, Johnson EJ, et al. View abstract. 2013 Jul;131(7):843-50. Int.J.Cancer 9-1-2012;131(5):1158-1168. Invest Ophthalmol.Vis.Sci. 2013;98(3):778-86. View abstract. Liver Cleanse | Lutein Benefits, Uses, Foods, Side Effects and More - Dr Chew EY, Clemons TE, SanGiovanni JP, et al. Ophthalmology 2012;119(11):2290-2297. J Aging Res 2019;2019:3709402. 2007;61(9):1121-1127. View abstract. Wilson LM, Tharmarajah S, Jia Y, Semba RD, Schaumberg DA, Robinson KA. Invest Ophthalmol.Vis.Sci. Objective: We investigated the association of maternal total intakes (foods + supplements) of 10 antioxidant nutrients during pregnancy with wheezing and eczema in 2-y-old children. Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies. Hammond, B. R., Jr., Fletcher, L. M., and Elliott, J. G. Glare disability, photostress recovery, and chromatic contrast: relation to macular pigment and serum lutein and zeaxanthin. Arch Ophthalmol 1993;111:761-72. It contains 20 mg of lutein, 4 mg of zeaxanthin, 408mg of vitamin C, 242.3mg of vitamin E, 30mg of zinc, and 1.5mg of copper. Are supplements really necessary to achieve benefits? Nutrient intake and cataract extraction in women: a prospective study. Flood, V., Rochtchina, E., Wang, J. J., Mitchell, P., and Smith, W. Lutein and zeaxanthin dietary intake and age related macular degeneration. Goodman, M. T., Kiviat, N., McDuffie, K., Hankin, J. H., Hernandez, B., Wilkens, L. R., Franke, A., Kuypers, J., Kolonel, L. N., Nakamura, J., Ing, G., Branch, B., Bertram, C. C., Kamemoto, L., Sharma, S., and Killeen, J. BMC Ophthalmol 2007;7:3. Spread supplemented with moderate doses of vitamin E and carotenoids reduces lipid peroxidation in healthy, nonsmoking adults. WebLutein & Zeaxanthin Eye Health Supplement for Adults - Delicious Vegan Eye Vitamins Lutein and Zeaxanthin Gummies - Zeaxanthin Plus Lutein 20mg for Vision Clarity Dry Eye Relief and Blue Light Support. Effect of the main dietary antioxidants (carotenoids, gamma-tocopherol, polyphenols, and vitamin C) on alpha-tocopherol absorption. Invest Ophthalmol.Vis.Sci. In the process, antioxidants like lutein protect healthy cells while halting the growth of malignant cells. Johnson, E. J. Dietary lutein plus zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and obesity. 2000;41(11):3322-3326. 2006;84(5):971-974. Am.J.Clin.Nutr. J Epidemiol. J Nutr 2022;152(11):2555-64. This daily supplementation decreased the risk of macular degeneration from intermediate to advanced stages by 25%. Lutein may help reduce these symptoms of age-related macular degeneration from intermediate to advanced by. 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