Agricultural Chemical. Aggregating chronic (or background) dietary exposure with short- and intermediate-term exposures, EPA has concluded that the combined food, water, and short- and intermediate-term residential exposures result in aggregate margins of exposures above the level of concern for all scenarios assessed and are not of concern. Wear suitable protective clothing. Each document posted on the site includes a link to the By inhibiting gibberellin, trinexapac-ethyl treatment reduces plant height thereby reducing the tendency to lean or fall over. New Documents UF, Residential LOC for MOE = 100 Employees. This document has been published in the Federal Register. Trinexapac-ethyl 11.3% Sl 25 Ec 95% Tc Trinexapac-ethyl Plant Growth Regulator , Find Complete Details about Trinexapac-ethyl 11.3% Sl 25 Ec 95% Tc Trinexapac-ethyl Plant Growth Regulator,Trinexapac-ethyl 11.3% Sl,Trinexapac-ethyl 25 Ec,Trinexapac-ethyl Plant Growth Regulator from Plant Growth Regulator Supplier or Manufacturer-Shanghai Sinogreatland Industrial Co., Ltd. We included an untreated check and ALL plots, including the check, received 10.5 oz/ac of Quilt Xcel at Feekes GS 10.5 (heading). Palisade did not affect lodging at Perkins. Evidence of increased susceptibility to offspring exists at or above the limit dose of the developmental and reproduction studies. Also, the Agency calculated dietary burden differently by using the highest residue measured in trials instead of the proposed tolerance level residues. Many applications of trinexapac-ethyl are mixed with an iron-containing product to mask bronzing that may occur. The Congressional Review Act, 5 U.S.C. Register (ACFR) issues a regulation granting it official legal status. Home; Product . However, to the best of our knowledge, TE has not been used to study the requirement of GAs in onset of germination. Relevant information about this document from Regulations.gov provides additional context. Developmental rabbit study. Trinexapac-ethyl is currently registered for the following uses that could result in residential exposures: Residential lawns, athletic fields, parks, and golf courses. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. This action does not involve any technical standards that would require Agency consideration of voluntary consensus standards pursuant to section 12(d) of the National Technology Transfer and Advancement Act of 1995 (NTTAA), Public Law 104-113, section 12(d) (15 U.S.C. You must file your objection or request a hearing on this regulation in accordance with the instructions provided in 40 CFR part 178. establishing the XML-based Federal Register as an ACFR-sanctioned If you have any questions regarding the applicability of this action to a particular entity, consult the person listed under FOR FURTHER INFORMATION CONTACT. Health considerations Accepted Delivery Terms. trinexapac-ethyl Chemical family: Cyclohexanecarboxylate Formulation: EC (Emulsifiable Concentrate) Product Overview Registration Application Advice Emergency Links and downloads Product overview MODDUS contains trinexapac-ethyl for use as a growth regulator in wheat, barley, oats, rye, triticale, durum wheat and ryegrass seed crops. Trinexapac-ethyl is a plant growth regulator that inhibits the formation of gibberellic acid and is used as an anti-lodging agent. documents in the last year, by the Centers for Medicare & Medicaid Services clothing Rinse skin immediately with plenty of water for 15-20 minutes. Section 408(b)(2)(D)(v) of FFDCA requires that, when considering whether to establish, modify, or revoke a tolerance, the Agency consider available information concerning the cumulative effects of a particular pesticide's residues and other substances that have a common mechanism of toxicity. EPA has not found trinexapac-ethyl to share a common mechanism of toxicity with any other substances, and trinexapac-ethyl does not appear to produce a toxic metabolite produced by other substances. In 2014 application of Palisade or Palisade plus Tilt significantlyreduced plant height at Chickasha and Perkins. Also, the tolerance for sugarcane, molasses is established at a different level than requested to conform with EPA's rounding class practice by removing the trailing zero. The analysis and recommendations made in this blog post are preliminary and based on research findings from 2013. A . 346a, any person may file an objection to any aspect of this regulation and may also request a hearing on those objections. Certain other material, such as copyrighted material, is not placed on the Internet and will be publicly available only in hard copy form. 95266-40-3 - RVKCCVTVZORVGD-QXMHVHEDSA-N - Trinexapac-ethyl [ISO] - Similar structures search, synonyms, formulas, resource links, and other chemical information. Trinexapac-ethyl CAS 95266-40-3 WIKI information includes physical and chemical properties, USES, security data, NMR spectroscopy, computational chemical data and more. Lose the iron and calcium. better and aid in comparing the online edition to the print edition. Lodging occurs due to a variety of factors, and as shown in the figure below, the timing of lodging will determine the final impact on grain yield. Wheat grain yield as affected by plant growth regulator in 2013, Wheat grain yield as affected by plant growth regulator in 2014. As a result, individuals can be exposed by entering these areas if they have been previously treated. =;Xb`0[,o DUv EPA will submit a report containing this rule and other required information to the U.S. Senate, the U.S. House of Representatives, and the Comptroller General of the United States prior to publication of this final rule in the Federal Register. In 2022, the global top five. The authority citation for part 180 continues to read as follows: Authority: on 1. To access the OCSPP test guidelines referenced in this document electronically, please go to http://www.epa.gov/ocspp and select Test Methods and Guidelines.. Pesticide Review Status. For hazards that have a threshold below which there is no appreciable risk, the toxicological POD is used as the basis for derivation of reference values for risk assessment. . This MRL is different than the tolerances established for trinexapac-ethyl in the United States. 3. 02/28/2023, 239 To summarize our work, we found a trend for one to two inch reductions in plant height when Palisade or Palisade plus Tilt were applied, but this did not consistently translate to increased grain yield. Manganese and trinexapac-ethyl are compatible and seem to yield higher turf growth suppression than trinexapac-ethyl and iron. TermsPrivacy NoticeOSU Agriculture Division 2022 Oklahoma State University. Therefore, acute aggregate risk is equivalent to the acute dietary risk as discussed in Unit III.C.1.i. In the rat reproduction study, reproductive toxicity was not observed, but decreased pup survival Start Printed Page 12742and decreased pup body weight/body-weight gain during lactation were observed above the limit dose with only reduced body weight and food consumption observed in the parental animals (>1,200 mg/kg/day). L. 104-4). The documents posted on this site are XML renditions of published Federal legal research should verify their results against an official edition of This document has been published in the Federal Register. name for 4-(cyclopropyl--hydroxymethylene)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester . Conversely, when larger carrier volumes are used, the coarser spray droplets result in reduced foliar coverage. . The Codex has established an MRL for trinexapac-ethyl in or on sugarcane at 0.5 ppm. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. Full disclosure: Syngenta donated the product for this trial, but the only funding for the research was provided by the Oklahoma Agricultural Experiment Station and the Oklahoma Cooperative Extension Service. on FederalRegister.gov The 90-day subchronic dog study showed decreased body weight gain and food consumption, diffuse thymic atrophy, and changes in the epithelial cells of the renal tubules at 516/582 milligrams/kilogram/day (mg/kg/day) (males/females). Any trinexapac-ethyl that hits the soil is lost. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National Institutes of Health Dietary exposure from food and feed uses. Bispyribac-sodium selectively controls annual bluegrass in cool-season turf but efficacy may be influenced by management practices, such as plant growth regulator use. The Codex Alimentarius is a joint U.N. Food and Agriculture Organization/World Health Organization food standards program, and it is recognized as an international food safety standards-setting organization in trade agreements to which the United States is a party. daily Federal Register on FederalRegister.gov will remain an unofficial ChemSpider ID 83439. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Uncertainty/safety factors (U/SF) are used in conjunction with the POD to calculate a safe exposure levelgenerally referred to as a population-adjusted dose (PAD) or a reference dose (RfD)and a safe margin of exposure (MOE). Chronic dietary risks are below the Agency's level of concern: 6.6% of the chronic population adjusted dose (cPAD) for children 1 to 2 years old, the population group receiving the greatest exposure. documents in the last year. We conducted the trial at Stillwater (Irr), Perkins (Irr), and Chickasha (Non-Irr). Mix in manganese. Please review additional information about the docket available at http://www.epa.gov/dockets. on The mutagenicity database is also complete, with no evidence of mutagenicity. Information about this document as published in the Federal Register. Trinexapac-ethyl Chemical Structures GB RN 1422 Trade Name LPI.A004 Label Indication Conventional Chemical CB RN 756428 Country USA Company LOVELAND PRODUCTS, INC. CAS RN 143294-89-7; 104273-73-6 Product Type Formulation IUPAC Name 4- [cyclopropyl (hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylic acid Compound Indication Acute dietary risks are below the Agency's level of concern: 2.5% of the acute population adjusted dose (aPAD) for females 13 to 49 years old, the population group of concern. What is trinexapac-ethyl? For information regarding EPA's efforts to determine which chemicals have a common mechanism of toxicity and to evaluate the cumulative effects of such chemicals, see EPA's Web site at http://www.epa.gov/pesticides/cumulative. Online edition to the acute dietary risk as discussed in Unit III.C.1.i entering these areas if they have been treated... -- hydroxymethylene ) -3,5-dioxo-cyclohexanecarboxylic acid ethyl ester of gibberellic acid and is used as an anti-lodging agent ( cyclopropyl hydroxymethylene... Have been previously treated offspring exists at or above the limit dose of the tolerance. Established an MRL for trinexapac-ethyl in or on sugarcane at 0.5 ppm previously treated trinexapac-ethyl are with... In 2014 application of Palisade or Palisade plus Tilt significantlyreduced plant height at Chickasha and Perkins properties, USES security! And other chemical information and more in 2013, wheat grain yield as by. 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